Welcome to Riley’s

Riley’s Drugs is named for the late Dr. Sid Riley, a Batesburg orphan and 1921 graduate of MUSC College of Pharmacy, who opened his first pharmacy in the Red Bank Mill village of Lexington in 1924. Lightning struck the pharmacy in the 1940’s causing it to burn and prompting him to rebuild Riley’s Drugs’ second location in 1947 on Columbia Avenue in Lexington. Doc was the friend, mentor, and eventual business partner to pharmacist Bob Perry who joined the Riley’s Drugs’ staff in 1967 after graduating from the USC College of Pharmacy. After 55 years of service to Riley’s Drugs and the town of Lexington, Bob is enjoying his retirement. Bob’s daughter, Roberta Perry Vining, a second-generation pharmacist and a 1987 graduate of the USC College of Pharmacy is the current owner of Riley’s Drugs. Roberta started working at Riley’s when she was in high school and was honored to have been mentored by both Dr. Riley and her dad, Dr. Perry. In 2012, Riley’s Drugs relocated just down the street to their current location at 1207 West Main Street in Lexington. Riley’s Drugs and staff have grown through the almost 100 years we’ve been in business, thanks to many old and new loyal customers. The longevity of our pharmacy comes from our commitment to quality patient care and unsurpassed customer service. Riley’s Drugs is where you get more than just a prescription and we invite you to come see for yourself. We would love to be your first-choice pharmacy!

compounding lab window
nash the dog

Riley’s History

Our goal at Riley’s is to provide you with fast, friendly and professional service for all your prescription, prescription compounding, home medical equipment and total body wellness needs. As the only independent, family-owned pharmacy serving the Lexington and surrounding areas since 1924, we have developed a reputation for providing service beyond the commonplace. Our pharmacists and staff invite you to experience and expect excellent service and competitive prices. We will transfer your current prescriptions from any pharmacy or contact your physician’s office for a new prescription. We offer many services so please let us know how we can best serve you. We treat you special because you are! The staff at Riley’s Drugs & Riley’s Vital Care simply connect with you like no other pharmacy. Our caring, confident, professional staff goes the extra mile when it comes to customer care. Riley’s Drugs uses up-to-date information and technology systems to improve efficiency and provide quality products and services.

Meet Our Team