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(803) 359 - 2587

We are pleased to announce our new Smart Phone App for Riley's Drugs. The app is available for both Android and iPhone. You can refill your prescriptions fast and convenient from the app as well as get detailed information and health news.

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We want to be your first choice pharmacy!!!

"Serving the community for good health"

History of

Riley’s Drugs is named for the late Dr. Mark Sidney “Sid” Riley, a Batesburg orphan who opened his first pharmacy on Main Street in Lexington in 1924. Lightning struck Riley’s second location in Red Bank and burned it, prompting him to rebuild the pharmacy on Columbia Avenue in 1947. Doc was the friend, mentor and eventual business partner to pharmacist Bob Perry who joined the Riley’s Drugs staff in 1967 after graduating from the USC College of Pharmacy. Today, Bob partners with his daughter, Roberta Vining, a second generation pharmacist and a 1987 graduate of USC College of Pharmacy. In 2012, Riley’s Drugs expanded just down the street to their current location at 1207 West Main Street in Lexington.

Riley’s Drugs and staff have grown over the years, thanks to many old and new loyal customers. The longevity of our pharmacy comes from our commitment to quality patient care and unsurpassed customer service. Riley’s Drugs is where you get more than just a prescription!

We invite you to experience the unique service and competitive prices here at Riley’s Drugs & Riley’s Vital Care. Few other places know your name, your family, your history and your friends like Riley’s. We’re a fast, friendly, reliable family pharmacy where modern-day convenience meets old-fashioned service